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How to treat recurrences after Avastin treatment for neovascular AMD: stick to Avastin or switch to Lucentis?
  1. A Wolf,
  2. D Kook,
  3. R Strauss,
  4. A Kampik,
  5. C Haritoglou
  1. Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany
  1. Dr A Wolf, Department of Ophthalmology, Ludwig-Maximilians-University, Mathildenstr. 8, 80336 München, Germany; armin.wolf{at}

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Before the recent approvement of ranibizumab (Lucentis) for the treatment of neovascular age-related macular degeneration (AMD), bevazicumab (Avastin) had been successfully used as an off-label treatment for this condition.1 As a consequence, in daily practice we are confronted with a large number of patients having received Avastin injections in the past, now facing a recurrence of the disease and therefore requiring additional injections.2 This leaves the ophthalmologist in a medical dilemma: should one continue with the off-label drug Avastin or switch to Lucentis? From a clinical point of view and disregarding the legal aspects of continuing …

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  • Competing interests: None.