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Tachosil: a new alternative for the treatment of non-traumatic corneal perforations
  1. M Hurtado-Sarrió1,
  2. A Duch-Samper2,
  3. A Cisneros-Lanuza1,
  4. M Díaz-Llopis1
  1. 1
    Ophthalmology Service, La Fe University Hospital, Valencia, Spain
  2. 2
    Ophthalmology Service, Arnau de Vilanova Hospital, Valencia, Spain
  1. Correspondence to Dr M Hurtado-Sarrió, Ophthalmology Service, La Fe University Hospital, Valencia, Spain, Esmeralda I, Casa 7, Mas Camarena, 46117 Betera, Valencia, Spain; hurtado_mer{at}

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TachoSil is a collagen sponge with human fibrinogen 5.5 mg, and human thrombin 2.0 IU.

Upon contact with physiological fluids or saline solution, the components of the coating dissolve and partly diffuse into the wound surface, creating a firm, mechanically stable network with good adhesive properties as well as sealing. Here we report the first case of the use of a collagen sponge combined with human fibrin sealant (TachoSil) in ophthalmology to patch a corneal perforation after infectious keratitis.

Case report

An 84-year-old Caucasian male with a history of heart disease treated with acenocoumarin and chronic obstructive pulmonary disease (COPD) reported to the emergency room with red eye, ocular pain, photophobia, decreased vision and discharge. At the slit-lamp examination, a large corneal stromal infiltrate with hypopyon was observed. A bacterial culture revealed Streptococcus pneumoniae. The keratitis responded to …

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  • Competing interests None.

  • Provenance and Peer review Not commissioned; externally peer reviewed.

  • Ethics approval Ethics approval was provided by the Educational and Investigation Department of La Fe University Hospital, Valencia (Spain).

  • Patient consent Obtained.