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Comments on 23-gauge versus 20-gauge system for pars plana vitrectomy
  1. A Sinha,
  2. R Narula,
  3. R Narayanan
  1. Retina & Vitreous Service, L V Prasad Eye Institute, Hyderabad, India
  1. Correspondence to Dr Anshuman, Smt Kannuri Santhamma Retina & Vitreous Service, L V Prasad Eye Institute, L V Prasad Marg, Banjara Hills, Hyderabad 500034, India; asn{at}

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We read with interest the paper by Wimpissinger et al, comparing the sutureless 23-gauge (23GA) system with a standard 20-gauge (20GA) system for pars plana vitrectomy, in a randomised clinical trial.1 We aim to highlight a few issues in the design, methodology and analysis.

The authors have analysed postoperative pain and conjunctival injection as primary outcome measures. The effort by the assessor to elicit a response on the degree of pain is likely to be biased if they are not masked, as in this study. …

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  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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  • PostScript
    S Binder B Wimpissinger L Kellner W Brannath K Krepler U Stolba C Mihalics