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An 8-year-old Italian girl with early-onset oligo-juvenile idiopathic arthritis (JIA) and bilateral anterior uveitis (AU), was treated at first with prednisone (0.5–1 mg/kg/day) and methotrexate (10 mg/m2/week), then, due to severe arthritis, with etanercept (0.4 mg/kg twice/week). Despite the improvement in arthritis, in 2 years’ time, the child underwent six relapses of bilateral AU with development of posterior synechiae and cystoid macular oedema (CMO).
Etanercept was then discontinued …
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