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The use of rituximab in refractory mucous membrane pemphigoid with severe ocular involvement
  1. A H Ross,
  2. P Jaycock,
  3. S D Cook,
  4. A D Dick,
  5. D M Tole
  1. Bristol Eye Hospital, Bristol, UK
  1. Mr A H Ross, Bristol Eye Hospital, Lower Maudlin Street, Bristol BS1 2LX, UK; adamross{at}

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Mucous membrane pemphigoid (MMP) with ocular involvement is part of a spectrum of autoimmune disease, associated with chronic inflammatory changes and mucous membrane blistering.


A 37-year-old gentleman presented to our clinic with a 3-month history of sore red eyes, treated with topical chloramphenicol for presumed bacterial conjunctivitis. During the preceding 3 months, he reported mouth and penile ulcers, dysphagia, hoarseness and blistering of plantar aspect of his right foot. Examination revealed …

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  • Competing interests: None.

  • Patient consent: Obtained.

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