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Unilateral leucocoria in clinically normal eyes
  1. R Batra1,
  2. F Rowe2,
  3. A Rowlands1,
  4. C Noonan1
  1. 1
    Department of Ophthalmology, North Cheshire Hospitals NHS Trust, Warrington, UK
  2. 2
    Division of Orthoptics, University of Liverpool, Liverpool, UK
  1. Miss R Batra, Birmingham and Midland Eye Centre, Dudley Road, Birmingham B18 7QH, UK; ruchikabatra{at}

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Leucocoria may be caused by cataract, retinal detachment, retinoblastoma and other intraocular abnormalities.1 A delay in the diagnosis of retinoblastoma can lead to local tumour invasion, blindness and even death.1 The presenting sign of retinoblastoma is commonly leucocoria which, despite routine paediatric screening, is usually initially detected by a parent.2

Seven children are described, three male and four female, who were referred due to unilateral leucocoria detected in amateur photographs. The mean age was 3 years (range 18 months to 4.5 years). Cases 2 and 3 were siblings. The remaining children were unrelated. Each case is outlined in table 1. In case 1, presented in fig 1, this alternated in subsequent photographs. In the remaining six cases, two demonstrated right leucocoria and four left leucocoria. In …

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  • Competing interests: None.

  • Patient consent: Obtained from the parents.

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