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The influence of disease severity on quality of eye-drop administration in patients with glaucoma or ocular hypertension
  1. F Aptel1,
  2. H Masset1,
  3. C Burillon1,
  4. A Robin2,
  5. P Denis1
  1. 1
    Department of Ophthalmology, Edouard Herriot Hospital, Lyon, France
  2. 2
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
  1. Dr F Aptel, Department of Ophthalmology, Edouard Herriot Hospital, 5, Place d’Arsonval, 69437 Lyon cedex 03, France; aptel_florent{at}

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Compliance in glaucoma patients is different from that in patients with most other systemic diseases for which the primary intervention involves either the oral administration of a pill or intravenous administration of a medication. Most individuals know how to take a pill; by contrast, the proper administration of eye-drops may be difficult for many patients. Numerous studies have focused on medication persistency and compliance,1 but few have examined whether the eye-drops that are administered actually get into the eye.2 3 Therefore, we investigated the quality of the topical eye-drop instillation technique in patients diagnosed as having open-angle glaucoma (OAG) or ocular hypertension (OHT) and assessed the relation between the ability to administer eye-drops properly and disease severity. A total of 138 patients with OAG (n = 87) or OHT (n = 51) treated with at least one topical ocular hypotensive medication for a minimum of 1 month were …

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  • Competing interests: None.

  • Ethics approval: Ethics approval was provided by The French Society of Ophthalmology Ethics Committee.

  • Patient consent: Obtained.