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National survey of the use of intraoperative antibiotics for prophylaxis against postoperative endophthalmitis following cataract surgery in the UK
  1. S Murjaneh1,
  2. S Waqar1,
  3. J E Hale2,
  4. M Kasmiya1,
  5. J Jacob1,
  6. A G Quinn1
  1. 1West of England Eye Unit, Exeter, UK
  2. 2Bristol Eye Hospital, Bristol, UK
  1. Correspondence to Dr Anthony G Quinn, West of England Eye Unit, Royal Devon and Exeter (Wonford) Hospital, Barrack Road, Exeter, Devon EX2 5DW, UK; anthony.quinn{at}

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Postoperative endophthalmitis (POE) is a serious complication after cataract surgery. The rate of endophthalmitis was reported in the British Ophthalmological Surveillance Unit (BOSU) study as 1/700 (0.14%) cataract operations.1 With regard to the peri-operative use of antibiotics, the BOSU recommended the use of subconjunctival cefuroxime.2 A Swedish national prospective survey reported POE in 0.053% of units that used intracameral antibiotics as a standard protocol. Of these units, 98.5% used intracameral cefuroxime.3

The European Society of Cataract and Refractive Surgeons (ESCRS) Endophthalmitis Study Group recommended the use of intracameral cefuroxime in 1 mg/0.1 ml normal saline and reported a POE rate of 0.06% in patients who had intracameral cefuroxime.4 The Royal College of Ophthalmologists professional guidance, updated June 2007, recommended considering the use of intracameral cefuroxime.

Three years following the ESCRS recommendations, we conducted a national survey to identify the level of application of ESCRS recommendations …

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  • Competing interests None.

  • Provenance and peer review Not commissioned; not externally peer reviewed.