Article Text

Download PDFPDF
Presence of paravascular lamellar holes in patients with idiopathic premacular fibrosis
  1. Noriaki Shimada,
  2. Kyoko Ohno-Matsui,
  3. Takeshi Yoshida,
  4. Manabu Mochizuki
  1. Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan
  1. Correspondence to Kyoko Ohno-Matsui, Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113, 113-8510 Japan; k.ohno.oph{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

We have demonstrated that paravascular lamellar holes were present in 80% of patients with macular retinoschisis (MRS) of highly myopic patients by multiple scans of optical coherence tomography (OCT).1 Although MRS develops only in highly myopic eyes, and idiopathic preretinal macular fibrosis (IPFs) in non-highly myopic eyes, there are many similarities between the two conditions. For example, a proliferation of cellular elements has been demonstrated on the remnants of vitreous cortex and inner limiting membrane in eyes with MRS2 and IPF.3 4 Thus, the purpose of this study was to determine whether paravascular lamellar holes are present in non-highly myopic eyes with IPF.

The clinical characteristics of the seven patients are shown in table 1. OCT …

View Full Text


  • Funding Supported in part by research grant 19659445 and 19390441 from the Japan Society for the Promotion of Science, Tokyo, Japan.

  • Competing interests None.

  • Ethics approval Ethics approval was provided by the Tokyo Medical and Dental University.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.