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Determination of treatment strategies for granular corneal dystrophy type 2 using Fourier-domain optical coherence tomography
  1. Tae-im Kim1,
  2. Jin Pyo Hong2,
  3. Byung Jin Ha3,
  4. R Doyle Stulting4,
  5. Eung Kweon Kim1
  1. 1Department of Ophthalmology, Corneal Dystrophy Research Institute, Yonsei University, College of Medicine, Seoul, Korea
  2. 2Saeyan Eye Clinic, Seoul, Korea
  3. 3Siloam Eye Hospital, Seoul, Korea
  4. 4Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
  1. Correspondence to Dr Eung Kweon Kim, Department of Ophthalmology, Yonsei University, College of Medicine, 134 Shinchon-dong, Seodaemun-ku, 120-752, Seoul, Korea; eungkkim{at}


Aim To evaluate the use of Fourier-domain optical coherence tomography (FD-OCT) in the selection and planning of surgical procedures to treat GCD2 (granular corneal dystrophy type 2).

Methods An RTVue-100 FD-OCT (Optovue, Fremont, California) was used to determine the size, depth and location of deposits in six patients with homozygous or heterozygous GCD2.

Results The RTVue-100 FD-OCT revealed the depth of the deposits quite precisely, allowing the determination of the appropriate depth of PTK (phototherapeutic keratectomy) and the appropriate selection of lamellar versus penetrating keratoplasty as the procedure of choice. In each case, visually significant opacities were adequately removed or would be removed.

Conclusion FD-OCT provides useful information for the selection and planning of surgical procedures to remove corneal opacities in patients with GCD2.

  • Cornea
  • dystrophy
  • imaging

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  • Funding This study was supported by the Korea Research Foundation grant 2008-KRF-531-E00048.

  • Competing interests None.

  • Ethics approval Ethics approval was provided by the Institutional Review Board of the College of Medicine, Yonsei University (No 4-2008-0331), Seoul, Korea.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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