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Multicentric malignant glioma of adulthood masquerading as optic neuritis
  1. Joseph G Chacko1,
  2. Byron L Lam2,
  3. Josna Adusumilli1,
  4. Sander R Dubovy2
  1. 1Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
  2. 2Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA
  1. Correspondence to Dr Joseph Chacko, Jones Eye Institute, University of Arkansas for Medical Sciences, 4301 W Markham #523, Little Rock, AR 72205, USA; jchacko{at}

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Malignant optic nerve glioma of adulthood is a rare tumour that can mimic optic neuritis in its initial presentation.1 2 At onset, unilateral decreased vision occurs in 70% of patients; however, a rapid progression to total blindness is usually seen within 3 months and death within 1 to 2 years.3 MRI often shows diffuse enhancement and, later, enlargement of the affected optic nerves, chiasm and tracts. We report a unique, multicentric case of malignant optic nerve glioma involving two exceptionally rare sites, the corpus callosum and cerebellum.

Case report

A previously healthy 48 year-old man was referred for blurry vision of the right eye with pain on eye movement for 1 week. …

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  • Funding Research to Prevent Blindness, Inc. and the Pat & Willard Walker Eye Research Center, UAMS, Little Rock, AR.

  • Competing interests None.

  • Patient consent Obtained.

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