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Letter
The conclusions of Clemson et al concerning valproic acid are premature
  1. Mary J van Schooneveld1,
  2. L Ingeborgh van den Born2,
  3. Mies van Genderen3,
  4. Jan-Geert Bollemeijer4
  1. 1Academic Medical Centre (AMC) and the Netherlands Institute for Neuroscience (NIN), Amsterdam, the Netherlands
  2. 2Eye Hospital, Rotterdam, the Netherlands
  3. 3Bartiméus Institute, Zeist, the Netherlands
  4. 4Leiden University Medical Centre, Leiden, the Netherlands
  1. Correspondence to Dr Mary J van Schooneveld, AMC and NIN, Amsterdam, Meibergdreef 47, Amsterdam 1100 AC, the Netherlands; mjschoone{at}xs4all.nl

https://doi.org/10.1136/bjo.2010.194373

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    We read the article of Clemson et al1 about a new treatment for retinitis pigmentosa (RP) with great interest. However, the authors' claim that their data suggest that valproic acid (VPA) may be an effective treatment for RP is unfounded and also regrettably misleading for the many desperate RP patients. In fact, we are …

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    Footnotes

    • Linked articles 195768, 175356.

    • Competing interests None to declare.

    • Provenance and peer review Not commissioned; not externally peer reviewed.

    Linked Articles

    • PostScript
      Authors' response
      Christine M Clemson Radouil Tzekov Jenna M Checchi Mark Krebs Shalesh Kaushal
      British Journal of Ophthalmology 2010; 95 153-154 Published Online First: 28 Oct 2010. doi: 10.1136/bjo.2010.195768
    • Clinical science
      Therapeutic potential of valproic acid for retinitis pigmentosa
      C M Clemson R Tzekov M Krebs J M Checchi C Bigelow S Kaushal
      British Journal of Ophthalmology 2010; 95 89-93 Published Online First: 20 Jul 2010. doi: 10.1136/bjo.2009.175356