Article Text

Download PDFPDF
Treatment of non-arteritic anterior ischaemic optic neuropathy
  1. Sohan Singh Hayreh
  1. Correspondence to Sohan Singh Hayreh, Department of Ophthalmology & Visual Sciences, College of Medicine, University of Iowa, Iowa City, IA 52242, USA; sohan-hayreh{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

I was interested to read the paper by Modarres and colleagues1 entitled “Intravitreal erythropoietin injection for the treatment of non-arteritic anterior ischaemic optic neuropathy” (NA-AION). The authors have made several misleading statements that require comment.

In my prospective study2 of visual outcome in 312 patients with NA-AION treated with corticosteroid therapy versus 301 untreated cases, there was a significantly higher visual acuity (p=0.001) and visual field (p=0.005) improvement in the treated than the untreated group. Modarres and colleagues commented that the claims of that study are not justified because of “lack of randomization, the retrospective nature of the study and the lack of corroboration via other studies”. None of these statements is correct: it was …

View Full Text


  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.