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I took great interest in the recent article regarding the retinal pigment epithelium (RPE) transplantation by Falkner-Radler et al.1 I agree that RPE cell transplantation might be a novel therapeutic option for patients in the antivascular endothelial growth factor (anti-VEGF) era, where anti-VEGF fails to improve visual acuity. This is the case in RPE tear,2 massive subretinal haemorrhage3 or anti-VEGF non-responders.
As already stated by the authors, transplantation of an RPE cell suspension has the disadvantage of …