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A reply to human retinal pigment epithelium (RPE) transplantation: outcome after autologous RPE-choroid sheet and RPE cell-suspension in a randomised clinical study
  1. Albert Caramoy
  1. Correspondence to Dr Albert Caramoy, University of Cologne, Center of Ophthalmology, Department of Vitreo-Retinal Surgery, Kerpener Str. 62, 50924 Cologne, Germany; acaramoy{at}

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I took great interest in the recent article regarding the retinal pigment epithelium (RPE) transplantation by Falkner-Radler et al.1 I agree that RPE cell transplantation might be a novel therapeutic option for patients in the antivascular endothelial growth factor (anti-VEGF) era, where anti-VEGF fails to improve visual acuity. This is the case in RPE tear,2 massive subretinal haemorrhage3 or anti-VEGF non-responders.

As already stated by the authors, transplantation of an RPE cell suspension has the disadvantage of …

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