Article Text

Download PDFPDF
The repeatability of the MPS 9000 macular pigment screener
  1. I J Murray,
  2. D Carden,
  3. M Makridaki
  1. University of Manchester, Manchester, UK
  1. Correspondence to Dr I J Murray, Moffat Building, Faculty of Life Sciences, University of Manchester, PO Box 88, Manchester M60 1QD, UK; Ian.j.murray{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Bartlett et al1 describe the clinical evaluation of the MPS 9000, which is designed to measure macular pigment optical density (MPOD) under clinical conditions. Their aim was to determine instrument variability (noise). Their conclusion, based on the coefficient of repeatability (COR), is that the instrument cannot reliably detect change less than 0.33 optical density (OD) units. This is poor and much worse than previous reports. There is a substantive literature illustrating the veracity of data generated by this instrument. It would have been helpful if the authors offered some comment on the discrepancy between their data and previous findings.

By extracting the raw data from figure 1 in Bartlett et al1 we have calculated the individual measurements for visits 1 and 2. In four out of 38 measurements, there is a difference of …

View Full Text


  • Linked articles 196386.

  • Competing interests IJM and DC developed the MPS 9000 and hold patent rights on the IP associated with the instrument.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; not externally peer reviewed.

Linked Articles