Article Text

Download PDFPDF
Original article
A new algorithm for automated nystagmus acuity function analysis
  1. Zheng Tai1,2,
  2. Richard W Hertle1,
  3. Richard A Bilonick1,
  4. Dongsheng Yang1
  1. 1The Laboratory of Visual and Ocular Motor Neurophysiology, The UPMC and Children's Eye Center, Department of Ophthalmology, Pediatric Ophthalmology, The Children's Hospital of Pittsburgh and University of Pittsburgh, Pittsburgh, Pennsylvania, USA
  2. 2Southwest Eye Hospital, Southwest Hospital, Third Military Medical University, Chongqing, China
  1. Correspondence to Dr Dongsheng Yang, The Ocular Motor Neurophysiology Laboratory, The UPMC Eye Center, Department of Ophthalmology, Pediatric Division, The Children's Hospital of Pittsburgh of UPMC and University of Pittsburgh, 3rd Floor, Room 3649, One Children Drive, 4401 Penn Avenue, Pittsburgh, Pennsylvania 15201, USA; yangd{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


Nystagmus is a relatively common oculomotor disorder in which vision is degraded by rhythmical, involuntary ocular oscillations.1 2 A nystagmus acuity function is often used to quantify effects of surgical or pharmaceutical intervention. To calculate the nystagmus acuity function for nystagmus patients, a series of parameters, such as foveation duration,3–6 foveation eye positions,5–10 mean velocity of nystagmus slow phase,11 and a combination of foveation eye positions and eye velocities12–14 have been used. Dynamic system analysis,15 fixed point analysis16 and wavelet spectrum17 18 have also been used for nystagmus acuity evaluation. A well-known method in the field of nystagmus research is the expanded nystagmus acuity function (NAFX). The NAFX uses both foveation eye position and eye velocity criteria to calculate acuity function according …

View Full Text


  • Funding This project has been partly supported by the Competitive Medical Research Fund (CMRF) from the University of Pittsburgh and by the Department of Ophthalmology, University of Pittsburgh.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Ethics approval This study was conducted with the approval of the Institutional Review Board of the University of Pittsburgh.

  • Provenance and peer review Not commissioned; externally peer reviewed.