Toxicological evaluation of preservative-containing and preservative-free topical prostaglandin analogues on a three-dimensional-reconstituted corneal epithelium system

Hong Liang; Aude Pauly; Luisa Riancho; Christophe Baudouin; Françoise Brignole-Baudouin

doi:10.1136/bjo.2010.189449

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Laboratory science

Original article

Toxicological evaluation of preservative-containing and preservative-free topical prostaglandin analogues on a three-dimensional-reconstituted corneal epithelium system

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	Abstract	Full	Pdf
Mar 2011	181	4	63
Apr 2011	159	50	105
May 2011	78	66	106
Jun 2011	65	85	75
Jul 2011	25	47	48
Aug 2011	21	32	28
Sep 2011	11	30	27
Oct 2011	20	42	36
Nov 2011	38	33	34
Dec 2011	30	37	29
Jan 2012	12	41	19
Feb 2012	16	41	27
Mar 2012	38	63	31
Apr 2012	17	38	26
May 2012	17	35	19
Jun 2012	17	37	21
Jul 2012	12	24	18
Aug 2012	6	31	8
Sep 2012	16	19	15
Oct 2012	18	60	14
Nov 2012	5	52	14
Dec 2012	6	17	14
Jan 2013	6	29	12
Feb 2013	3	11	10
Mar 2013	9	32	16
Apr 2013	10	13	13
May 2013	13	21	14
Jun 2013	25	13	9
Jul 2013	12	14	5
Aug 2013	7	14	5
Sep 2013	6	5	6
Oct 2013	6	30	11
Nov 2013	14	27	7
Dec 2013	15	31	10
Jan 2014	12	13	0
Feb 2014	19	7	5
Mar 2014	21	13	2
Apr 2014	25	33	4
May 2014	44	39	6
Jun 2014	22	26	8
Jul 2014	23	16	11
Aug 2014	19	12	7
Sep 2014	12	9	3
Oct 2014	8	14	13
Nov 2014	15	14	3
Dec 2014	12	13	8
Jan 2015	17	9	10
Feb 2015	3	7	6
Mar 2015	14	14	4
Apr 2015	8	6	4
May 2015	5	8	2
Jun 2015	2	5	7
Jul 2015	3	3	5
Aug 2015	12	8	1
Sep 2015	14	12	8
Oct 2015	7	0	2
Nov 2015	24	4	5
Dec 2015	14	2	4
Jan 2016	8	4	9
Feb 2016	4	12	7
Mar 2016	6	5	12
Apr 2016	7	4	5
May 2016	6	6	3
Jun 2016	6	5	4
Jul 2016	13	1	10
Aug 2016	9	3	5
Sep 2016	18	6	5
Oct 2016	13	4	5
Nov 2016	11	3	4
Dec 2016	10	3	14
Jan 2017	10	4	4
Feb 2017	4	4	4
Mar 2017	7	13	1
Apr 2017	6	14	3
May 2017	3	27	8
Jun 2017	6	8	8
Jul 2017	9	9	6
Aug 2017	28	20	7
Sep 2017	69	57	5
Oct 2017	141	136	2
Nov 2017	51	47	4
Dec 2017	43	37	4
Jan 2018	26	20	5
Feb 2018	60	40	10
Mar 2018	32	28	8
Apr 2018	40	30	6
May 2018	48	30	5
Jun 2018	46	26	3
Jul 2018	51	35	2
Aug 2018	57	43	4
Sep 2018	62	41	1
Oct 2018	35	27	1
Nov 2018	46	34	9
Dec 2018	49	37	3
Jan 2019	38	28	8
Feb 2019	37	24	6
Mar 2019	34	20	6
Apr 2019	241	235	10
May 2019	35	19	11
Jun 2019	35	25	10
Jul 2019	40	16	14
Aug 2019	44	28	15
Sep 2019	34	29	6
Oct 2019	32	28	6
Nov 2019	43	35	7
Dec 2019	84	36	10
Jan 2020	84	26	4
Feb 2020	29	23	7
Mar 2020	43	37	11
Apr 2020	38	30	11
May 2020	34	32	10
Jun 2020	29	27	7
Jul 2020	35	29	6
Aug 2020	20	16	4
Sep 2020	46	34	5
Oct 2020	44	42	9
Nov 2020	28	24	7
Dec 2020	59	38	5
Jan 2021	19	12	9
Feb 2021	17	9	10
Mar 2021	10	8	8
Apr 2021	12	10	14
May 2021	12	10	10
Jun 2021	11	11	8
Jul 2021	8	8	7
Aug 2021	7	7	14
Sep 2021	8	8	8
Oct 2021	23	12	20
Nov 2021	22	19	28
Dec 2021	10	10	4
Jan 2022	19	15	6
Feb 2022	20	14	6
Mar 2022	49	29	16
Apr 2022	33	23	10
May 2022	36	35	21
Jun 2022	27	26	14
Jul 2022	17	15	3
Aug 2022	23	26	10
Sep 2022	52	40	10
Oct 2022	21	18	17
Nov 2022	22	20	11
Dec 2022	16	10	6
Jan 2023	29	23	12
Feb 2023	8	8	1
Mar 2023	7	7	5
Apr 2023	7	7	5
May 2023	10	8	11
Jun 2023	11	11	4
Jul 2023	11	11	13
Aug 2023	12	10	12
Sep 2023	16	16	5
Oct 2023	18	17	1
Nov 2023	20	18	10
Dec 2023	25	23	8
Jan 2024	40	41	8
Feb 2024	5	5	29
Mar 2024	26	25	21
Total	4254	3740	1829

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