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Trabeculectomy with mitomycin C in advanced glaucoma
Stead and King determined the medium-term intraocular pressure (IOP) control and visual outcomes in 103 patients with advanced glaucoma (MD −20 dB or above) undergoing trabeculectomy with mitomycin C. At 5 years, 85% had IOP of <16 mm Hg, and 96% had an IOP of <21 mm Hg. Mean MD for the group as a whole and for individual patients remained stable. Twenty-seven per cent patients experienced a significant reduction in acuity (attributable to trabeculectomy in about 10% of cases). The only preoperative determinant for reduction in VA was a low preoperative MD. (See page 960)
Adjuvant 5-fluorouracil for localised OSSN
Rudkin and Muecke prospectively studied outcome of localised non-invasive ocular surface squamous neoplasia (OSSN) wherein topical 5-fluorouracil (5-FU 1%) was used as an adjuvant to surgical excision and cryotherapy. Fifty-five cases were primary and 10 cases were of recurrent tumours. Surgical margins were involved in 29% of primary and 60% of recurrent cases. Irrespective of the surgical margins, a single cycle of …
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