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  1. Siamak Zarei-Ghanavati1,
  2. Mehran Zarei-Ghanavati1,
  3. Arturo Ramirez-Miranda2
  1. 1Cornea Department and Eye Research Center, Khatam-al-Anbia Eye Hospital, Mashhad University of Medical Sciences (MUMS), Mashhad, Iran
  2. 2Department of Cornea and Refractive Surgery, Institute of Ophthalmology “Conde de Valenciana”, National Autonomous University of Mexico, Mexico DF, Mexico
  1. Correspondence to Dr Siamak Zarei-Ghanavati, Mashhad University of Medical Sciences (MUMS), Khatam-al-Anbia Eye Hospital, Cornea Department and Eye Research Center, Abootaleb Blvd, Mashhad, Iran; zareis{at}

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We thank Busin et al1 for their letter regarding our article ‘Reverse big bubble: a new technique for preparing donor tissue of Descemet membrane endothelial keratoplasty’2 and would like to answer briefly the main questions raised.

Regarding their claim of novelty, we recently read their study regarding air-assisted donor preparation for Descemet membrane endothelial keratoplasty (DMEK) published in August 2010,3 but we were not aware of their presentation at the American …

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  • Provenance and peer review Not commissioned; not externally peer reviewed.

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