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24-hour ocular perfusion pressure in glaucoma patients
  1. Kaweh Mansouri1,
  2. Mauro T Leite1,2,
  3. Robert N Weinreb1
  1. 1Department of Ophthalmology, Hamilton Glaucoma Center, University of California San Diego, La Jolla, California, USA
  2. 2Hamilton Glaucoma Center La Jolla, University of California San Diego, California, USA
  1. Correspondence to Dr Kaweh Mansouri, University of California San Diego, Hamilton Glaucoma Center, 9500 Gilman Drive 0946, La Jolla, CA 92093-0946, USA; kawehm{at}

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We read with great interest the study by Costa and co-workers1 in which they compared 24--hour intraocular pressure (IOP) monitoring and ocular perfusion pressure (OPP) of glaucoma patients with healthy individuals. With recent literature mainly concentrated on 24-hour IOP, the authors are to be complimented for addressing the question of OPP and its relation to IOP. In glaucoma patients, they found higher systolic perfusion pressures in the morning and higher diastolic perfusion pressures during the night. However, their results can be questioned, as their method of calculating OPP does not account for positional influences.

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  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.