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Gamma knife radiosurgery for primary orbital varices: a preliminary report
  1. Desheng Xu1,
  2. Dong Liu1,
  3. Zhiyuan Zhang1,
  4. Yipei Zhang1,
  5. Guoxiang Song2
  1. 1Gamma Knife Center, Department of Neurosurgery, Tianjin Medical University Second Hospital, Tianjin, PR China
  2. 2Gamma Knife Center, Department of Ophthalmology, Tianjin Medical University Second Hospital, Tianjin, PR China
  1. Correspondence to Professor Dong Liu, Gamma Knife Center, Department of Neurosurgery, Tianjin Medical University Second Hospital, 23# Pingjiang Road, Hexi District, Tianjin, PR China, 300211; liu{at}


Aim The aim of this retrospective study is to evaluate the authors' experience using gamma knife radiosurgery in the management of primary orbital varices.

Methods Fourteen patients, six males and eight females, with ages ranging from 7 to 56 years of age, were treated with gamma knife radiosurgery from April 2001 to June 2005 for primary orbital varices. The median prescription peripheral dose was 16 Gy, ranging from 15 to 20 Gy, and the median maximum dose was 32 Gy, ranging from 30 to 40 Gy. The median volume of the lesion at radiosurgery was 4.5 ml (range 1.9 ml to 9.0 ml). The mean dose to optic nerve was below 10 Gy. A mean of 10 isocentres (range 8 to 13) were used for treating these lesions.

Results At a median follow-up period of 36 months (range 18 to 66 months), recurrent exophthalmos and diplopia resolved in 10 patients. Two of the remaining four patients showed evidence of decrease in distensibility, while the other two remain unchanged. The median time of their presenting symptoms resolving was 7 months (range 3 to 18 months). One patient lost her sight 18 months after gamma knife radiosurgery. No patient had intraorbital haemorrhage after treatment.

Conclusion Gamma knife radiosurgery provides effective long-term relief of symptoms in selected patients with primary orbital varices.

  • Gamma knife
  • radiosurgery
  • primary orbital varices
  • follow-up
  • orbit
  • treatment other

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  • DX and DL contributed equally to the work and should be considered equivalent first authors.

  • Competing interests None.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.