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Femtosecond laser-assisted lock-and-key shaped penetrating keratoplasty
  1. S S M Fung,
  2. A Iovieno,
  3. V A Shanmuganathan,
  4. V Chowdhury,
  5. Vincenzo Maurino
  1. Corneal and External Diseases Service, Moorfields Eye Hospital, London, UK
  1. Correspondence to Dr Vincenzo Maurino, Moorfields Eye Hospital, 162 City Road, London EC1V 2PD, UK; vincenzo.maurino{at}

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The advent of the femtosecond laser in ophthalmology allows precise and customised corneal graft configurations at the graft-host junction. Recent studies have yielded a variety of wound shapes, all of which increase the surface area at the graft-host junction, resulting in better wound approximation, faster healing and earlier suture removal with comparable or reduced astigmatism.1–5 Among them, the mushroom and top hat configurations have been shown to be mechanically more stable than the traditional penetrating keratoplasty (PK) and other wound shapes when sutures were applied.5 This enhanced stability was attributed to the peripheral flange that acts as a valve and prevents wound leakage.

In this study, we developed a novel ‘lock-and-key’ configuration for PK …

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  • Funding The study was funded in part by an unrestricted grant from Abbott Medical Optics. The sponsor has no role in study design and collection, analysis and interpretation of data. The authors have no financial interests or commercial affiliations.

  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.