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Gender differences in re-epithelialisation time in fungal corneal ulcers
  1. Tiruvengada Krishnan1,
  2. N Venkatesh Prajna2,
  3. Karsten Gronert3,
  4. Catherine E Oldenburg4,
  5. Kathryn J Ray4,
  6. Jeremy D Keenan4,
  7. Thomas M Lietman4,
  8. Nisha R Acharya4
  1. 1Aravind Eye Care System, Pondicherry, India
  2. 2Aravind Eye Care System, Madurai, India
  3. 3Vision Science School, School of Optometry, University of California, Berkeley, California, USA
  4. 4FI Proctor Foundation, University of California San Francisco (UCSF), San Francisco, California, USA
  1. Correspondence to Dr Nisha R Acharya, FI Proctor Foundation, Room S309, 513 Parnassus Avenue, UCSF, San Francisco, CA 94143-0412, USA; nisha.acharya{at}

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Animal studies have demonstrated that female mice may have a slower re-epithelialisation following corneal injury compared with males.1 However, it is unknown if this translates to humans. In this report, we compare re-epithelialisation time in men and women using data collected as part of a prospective, randomised clinical trial on fungal corneal ulcers.


Clinical outcome measures were obtained in a standardised manner from a clinical trial on fungal corneal ulcers, which has been previously described.2 Patients were …

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  • Funding Funding for this research was from That Man May See and the South Asia Research Fund. NRA is supported by a National Eye Institute K23EY017897 grant and a Research to Prevent Blindness Career Development Award. TML is supported by a National Eye Institute grant U10-EY015114 and a Research to Prevent Blindness award.

  • Competing interests None.

  • Ethics approval Ethical approval was obtained from the University of California, San Francisco and the Aravind Eye Care System.

  • Provenance and peer review Not commissioned; internally peer reviewed.