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Long-term visual outcomes following lens-sparing vitrectomy for retinopathy of prematurity
  1. Ruhi Singh1,
  2. Deepthi M Reddy2,
  3. Andrew Jonathan Barkmeier3,
  4. Eric R Holz4,
  5. Radha Ram5,
  6. Petros Euthymiou Carvounis1
  1. 1Alkek Eye Center, Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, USA
  2. 2Department of Ophthalmology, University of Alabama, Birmingham, Alabama, USA
  3. 3Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA
  4. 4Department of Ophthalmology, Retina Vitreous Texas, Houston, Texas, USA
  5. 5School of Medicine, Baylor College of Medicine, Houston, Texas, USA
  1. Correspondence to Professor Petros Euthymiou Carvounis, Alkek Eye Center, Baylor College of Medicine, 1977 Butler Blvd, Houston, TX 77030, USA; carvounis{at}yahoo.comPreviously presented at ARVO 2010, American Society of Retina Specialists 2010 and American Academy of Ophthalmology 2010.


Aim To describe the long-term outcomes of lens-sparing vitrectomy (LSV) for retinopathy of prematurity (ROP).

Methods Single-centre retrospective case series of eyes that underwent LSV for ROP between 1998 and 2005 and had a follow-up of at least 5 years. The primary outcome was the mean visual acuity, and secondary outcomes were the proportion of eyes without functional vision, proportion of eyes with anatomic success, proportion of Stage 4A eyes with vision better than 20/400, proportion of Stage 4B eyes with vision better than 20/800.

Results Thirty-seven eyes of 30 patients (mean age at last follow-up: 7.1 years) were included in the study, while an additional 23 patients had been lost to follow-up and were not included in the study. Of eyes that underwent LSV for Stage 4A or 4B: 63% had measurable visual acuity (mean logMAR 0.92 for Stage 4A, 1.63 for Stage 4B), 19% had form vision, but neurological comorbidities precluded visual acuity measurement, and the remaining 18% had light perception or no light perception.

Conclusions While most eyes that underwent LSV for Stage 4A or 4B ROP maintain useful vision with long-term follow-up, approximately one-fifth of eyes had no functional vision, and in a further fifth, vision could not be measured due to severe neurological impairment.

  • Retina
  • Child health (paediatrics)

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