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Authors' response
  1. Luiz Vicente Rizzo1,
  2. Adriana Lima Vallochi2,
  3. Rubens Belfort3,
  4. Gary N Holland4,5,
  5. Robert B Nussenblatt6
  1. 1Hospital Israelita Albert Einstein, São Paulo, Brazil
  2. 2Instituto Oswaldo Cruz, Rio de Janeiro, Brazil
  3. 3Department of Ophthalmology, Escola Paulista de Medicina—Federal University of São Paulo, São Paulo, Brazil
  4. 4Ocular Inflammatory Disease Center, Jules Stein Eye Institute, UCLA, Los Angeles, California, USA
  5. 5Department of Ophthalmology, David Geffen School of Medicine, UCLA, Los Angeles, California, USA
  6. 6Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA
  1. Correspondence to Luiz Vicente Rizzo, Av Albert Einstein 627/701, Morumbi São Paulo, SP, Brazil, CEP 05652-000, lvrizzo{at}

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We would like to thank Dr Park1 for his comments on our work and for bringing these issues to our attention and of the other readers of the British Journal of Ophthalmology. All the points that were made are valid and we will strive to evaluate them properly and better our research. His interpretations with respect to all three points raised are correct. Regarding patient 16, the sample is negative by PCR analysis, which was wrongly indicated in the text as positive, but as pointed out by Dr Park, this does not detract from our findings. We thank Dr Park for highlighting that our study is innovative and provides new insight into the pathogenesis of ocular toxoplasmosis.



  • Funding This work was supported by FAPESP, grant number 98/11205, 06/53772-7 and CNPq 03763/2010-8.

  • Competing interests None.

  • Ethics approval The Ethics Committee at the Instituto de Ciências Biomédicas Universidade de São Paulo.

  • Provenance and peer review Commissioned; internally peer reviewed.