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- Experimental and #8211 animal models
- field of vision
- intraocular pressure
- aqueous humour
- optic nerve
Optical coherence tomography (OCT) has gained popularity in clinical ophthalmic management by providing detailed visualisation and quantification of ocular structures. The most common clinical use of this technology is in glaucoma, retina diseases, neuro-ophthalmology and anterior segment applications. Recent technological improvement leads to the introduction of spectral-domain OCT (SD-OCT) that offers higher scanning speeds, higher scan densities and better resolution than earlier generations of this technology. The ability to visualise areas of interest with a high acquisition rate SD-OCT imager along with the ability to quantify structures expands the utility of OCT to new clinical territories, such as children and other poorly compliant populations. In order to make full use of the OCT information, a comparison with population-derived normative data is needed to identify deviations from the normal range. Unfortunately, only limited information is available for persons <18 years of age for any of the commercially available OCTs.
Several studies have demonstrated that the retina and optic nerve change with ageing. This finding was …
Funding This study is supported in part by National Institutes of Health R01-EY013178, P30-EY008098 (Bethesda, MD); Eye and Ear Foundation (Pittsburgh, PA); Research to Prevent Blindness (New York, NY).
Competing interests JSS receives royalties for intellectual property licensed by Massachusetts Institute of Technology and Massachusetts Eye and Ear Infirmary to Carl Zeiss Meditec, Inc.
Provenance and peer review Commissioned; internally peer reviewed.