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Original article
Visual performance of the Akreos Adapt AO intraocular lens in patients with different corneal profiles measured with an adaptive optics visual simulator
  1. David Madrid-Costa1,
  2. Javier Ruiz-Alcocer2,
  3. Santiago García-Lázaro1,
  4. César Albarrán-Diego1,
  5. Robert Montés-Micó1
  1. 1Optometry Research Group (GIO), Optics Department, University of Valencia, Spain
  2. 2Optics and Optometry Department, Universidad Europea de Madrid, Spain
  1. Correspondence to Dr David Madrid-Costa, Optometry Research Group, Optics Department– University of Valencia, C/ Dr Moliner, 50, 46100 Burjassot, Spain;{at}


Aims To evaluate the visual performance of an aberration-free intraocular lens (IOL) in patients with different corneal profiles using adaptive optics visual simulation.

Methods A crx1 adaptive optics visual simulator was used to simulate the aberration pattern of an aberration-free IOL combined with five corneal profiles: virgin corneas and corneas with low and high myopic ablations and low and high hyperopic ablations. Ten eyes of 10 subjects were evaluated, and monocular distance visual acuity (VA) at 100%, 50% and 10% of contrast was measured.

Results At 100% of contrast, no differences were found in VA values among virgin corneas, low and high myopic ablations and low hyperopic ablation groups (p=0.06). All these groups achieved better results than the high hyperopic ablation group (p<0.001). At 50% and 10%, the best values of VA were obtained for the virgin corneas and for the low myopic and low hyperopic ablation groups (p>0.1, for both levels of contrast). Significant differences were found between these three corneal profiles and the other two corneal profiles (p<0.002 for high myopic and p<0.001 for high hyperopic, for both levels of contrasts).

Conclusions The results suggest that the aberration-free IOL design gives an excellent visual performance for a range of corneal spherical aberrations that could correspond to patients with virgin corneas and patients in which the corneal spherical aberration has been slightly modified by a hyperopic or myopic laser ablation.

  • Visual quality
  • aberration-free IOL
  • visual simulation
  • optics and refraction
  • lens and zonules
  • cornea

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  • Disclosure The authors have no proprietary interest in any of the materials mentioned in this article.

  • Funding This research was supported in part by a Ministerio de Ciencia e Innovación Research Grants (SAF2008-01114 and SAF2009-13342) and a José Castillejo scholarship to RM-M.

  • Competing interests None.

  • Patient consent Obtained.

  • Ethics approval Ethics approval was provided by University of Valencia.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement We declare that in this original research article we have exposed all our available data and that we do not have additional unpublished data.