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Immunosuppression for Mooren's ulcer
Ashar, Mathur and Sangwan evaluated step ladder approach for immunosuppressive treatment of Mooren's ulcer. Topical steroids used as a single therapy had a disease resolution rate of 76%. Cases that required oral steroids, oral methotrexate, intravenous pulsed methyl prednisolone and combination of pulsed methyl prednisolone and cyclophosphamide had a resolution rate of 86%, 79%, 71% and 73%, respectively. An aggressive immunosuppressive regimen based on disease severity as a first line of therapy improves the chances of disease control even in cases of aggressive Mooren's ulcer.
Contrast-enhanced intraoperative OCT
Ehlers et al describe the novel application of triamcinolone as an OCT contrast agent for intraoperative OCT to improve visibility of tissue interfaces and planes (eg, posterior hyaloid insertion points). The application of this technology may have wide-ranging implications for enhanced image-guided surgery, intraoperative OCT and dynamic or functional applications of OCT technology.
Stromal bed quality and endothelial damage after femtosecond laser cuts
Kimakura et al evaluated the stromal bed quality and …