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The potential for and challenges of spherical and chromatic aberration correction with new IOL designs
  1. Norberto López-Gil1,
  2. Arthur Bradley2
  1. 1Grupo de Ciencias de la Visión, Facultad de Óptica y Optometría, Universidad de Murcia, Murcia, Spain
  2. 2Indiana University School of Optometry, Bloomington, Indiana, USA
  1. Correspondence to Dr Norberto López-Gil, Facultad de Óptica y Optometría, Universidad de Murcia, Murcia 30100, Spain; norberto{at}

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When describing the human eye, celebrated scientist Hermann von Helmholtz once wrote1 ‘Now it is not too much to say that if an optician wanted to sell me an instrument which had all these defects, I should think myself quite justified in blaming his carelessness in the strongest terms, and giving him back his instrument’.

Helmholtz's assertion about the optics of the eye was quantified about a century later by Smirnov2 in Russia and the Howland brothers in the US, who found that normal human eyes exhibit significant levels of high-order aberrations, which can be much higher in eyes with corneal pathology, for instance, keratoconus.3 Laboratory studies and modern clinical aberrometers have allowed a large number of eyes to be measured in the last decade showing that aberrations of the unaccommodated eye are dominated by low-order (spherocylindrical refractive errors), third-order (coma and trefoil) and fourth-order spherical aberration4 (SA), as well as chromatic aberrations.5

From the perspective of an optical design, therefore, Helmholtz was correct, since the average human eye with pupil diameters larger than 5 mm has more than 10 times the monochromatic aberrations of typical optical instruments, which normally fulfil Marèchal's criterion (root mean square (RMS)<λ/14). Moreover, in polychromatic light, the quality of the retinal image can be even worse due to the significant amount of chromatic aberration presented in every eye, >2D between both extremes of the visible expectrum.6

Although all human eyes have significant monochromatic aberrations, the population mean for many of these aberrations is approximately zero.7 The notable exception is SA and, therefore, a correction for the population average SA could improve retinal image quality for most eyes. However, the positive SA observed in unaccommodated eyes, becomes significantly negative when accommodating,8 and thus, a SA correction that improved image …

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  • Contributors Both authors have equally contributed to every part of the manuscript.

  • Competing interests This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.

  • Provenance and peer review Commissioned; internally peer reviewed.