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Contributors RED took part in conception and design, drafting the article and final approval of the version to be published. JSS took part in conception and design, revising the article critically for important intellectual content and final approval of the version to be published.
Funding Supported in part by National Institutes of Health contract P30-EY08098 (Bethesda, MD, USA), The Eye and Ear Foundation (Pittsburgh, PA, USA) and an unrestricted grant from Research to Prevent Blindness (New York, NY, USA).
Competing interests JSS receives royalties for intellectual property licensed by Massachusetts Institute of Technology and Massachusetts Eye and Ear Infirmary to Carl Zeiss Meditec, Inc.
Provenance and peer review Commissioned; internally peer reviewed.