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Light chain deposition disease (LCDD) is a rare form of monoclonal gammopathy, characterised by deposits of either kappa or gamma light chains (LC) most frequently in the kidney, causing renal failure.1 LCDD is diagnosed by immunohistochemistry and transmission electron microscopy of renal biopsies.2 The frequency of ocular disease is not known (personal communication, National Amyloidosis Centre, University College London). Retinal vasculopathy such as hyperviscosity syndrome has previously been reported in association with LCDD.3 ,4 A recent case series of three patients with LCDD described retinal pigment epithelial (RPE) detachments and tears with subsequent retinal haemorrhage, fibrosis and degeneration due to LC deposition.5 We present a patient with subretinal haemorrhage and serous macular detachment secondary to choroidal neovascularisation but without pigment epithelial detachment …
Contributors Patient referred by ND; case written by SDK and MAM.
Competing interests None.
Provenance and peer review Not commissioned; internally peer reviewed.
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