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Visualisation of contrast-enhanced intraoperative optical coherence tomography with indocyanine green
  1. Justis P Ehlers1,
  2. Stephen McNutt1,
  3. Suhail Dar2,
  4. Yuankai K Tao1,
  5. Sunil K Srivastava1
  1. 1Cole Eye Institute, Ophthalmic Imaging Center, Vitreoretinal Service, Cleveland Clinic Foundation, Cleveland, Ohio, USA
  2. 2Case Western Reserve School of Medicine, Cleveland, Ohio, USA
  1. Correspondence to Dr Justis P Ehlers, Cole Eye Institute, Ophthalmic Imaging Center, Cleveland Clinic, 9500 Euclid Avenue/i32, Cleveland, OH 44195, USA; ehlersj{at}


Optical coherence tomography (OCT)-based visualisation of ophthalmic anatomy has transformed the clinical practice of ophthalmology. The translation of OCT into the surgical theatre is currently being actively researched and may provide a paradigm shift in surgical practice. Enhanced visualisation of tissues and tissue planes may provide further iterative improvement in surgeon feedback. Contrast-enhanced intraoperative OCT (iOCT) has been previously described with triamcinolone. In this report, we describe the OCT features and contrast enhancement noted with indocyanine green using iOCT in human subjects as well as an ex vivo analysis in porcine eyes.

  • Imaging
  • Treatment Surgery

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