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Conjunctival keratoacanthoma
  1. Patrick Oellers,
  2. Carol L Karp,
  3. Rikin R Shah,
  4. Marc Winnick,
  5. Jared Matthews,
  6. Sander Dubovy
  1. Bascom Palmer Eye Institute, University of Miami, Miami, Florida, USA
  1. Correspondence to Professor Carol L Karp, Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, 900 NW 17th Street, Miami, FL 33136, USA; ckarp{at}


An 83-year-old man presented with a 1-month history of a rapidly enlarging conjunctival mass. On examination, slit lamp biomicroscopy revealed a leukoplakic tumour at the temporal limbus. The lesion was excised with cryotherapy application to the limbus and conjunctival margins. Histopathology revealed a keratoacanthoma (KA). KA typically occurs on sun-exposed areas of the skin. Conjunctival KA is very rare, and differentiation between conventional squamous cell carcinoma (SCCA) and KA can be challenging. The present case highlights the indication for excisional surgery in patients with conjunctival KA using the no touch technique, cryotherapy, amniotic membrane and the histopathological differentiation between KA and SCCA.

  • Conjunctiva
  • Cornea
  • Treatment Surgery
  • Ocular surface
  • Pathology

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