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Central toxic keratopathy: a clinical case series
  1. Montserrat Garcia-Gonzalez1,
  2. Miguel A Teus2,3
  1. 1 Vissum Santa Hortensia, Madrid, Spain
  2. 2 Hospital Universitario ‘Príncipe de Asturias’, University of Alcalá, Alcalá de Henares, Madrid, Spain
  3. 3 Novovisión Madrid, Madrid, Spain
  1. Correspondence to Dr Montserrat Garcia-Gonzalez, Vissum Santa Hortensia, Santa Hortensia 58, Madrid 28002, Spain; montseggonz{at}

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Dear Editor,

We read with great interest the article by Marí Cotino and associates1 about an epidemic of central toxic keratopathy (CTK) that occurred after laser in situ keratomileusis (LASIK), presumably caused by the change of the brand of the surgical gloves. Although its aetiology is unknown, CTK has common features with grade IV diffuse lamellar keratitis, but it is widely accepted that it represents a separate clinical entity. It has received other names in the literature, such as ‘central flap necrosis’.

Marí Cotino et al 1 state in their article that CTK does not have a specific treatment and that the clinician must …

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