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Are lens implant modifications the best way to prevent posterior capsule opacification?
  1. Florian T A Kretz,
  2. Gerd U Auffarth
  1. David J Apple Laboratory of the Department of Ophthalmology, International Vision Correction and Research Centre (IVCRC), University Hospital Heidelberg, Heidelberg, Germany
  1. Correspondence to Florian T A Kretz, International Vision Correction and Research Centre & David J Apple Laboratory, Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; florian.kretz{at}

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Posterior capsule opacification (PCO) is the most common complication in intraocular lens surgery, occurring months to years after uncomplicated cataract surgery, and decreasing visual acuity significantly.1–4 A common and objective method to evaluate PCO is the EPCO software developed by Tetz et al,5 which has become widely accepted for PCO grading.6–11 The pathogenesis of PCO has been studied over several years, and several influential factors have been found. Different causes affect the migration and proliferation of residual lens epithelial cells from the periphery to the central area of the posterior capsular bag, changing light distribution and causing light scattering, and leading to reduced visual function.6–19

Different procedures have been tried to …

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  • Contributors The two authors have designed, written and reviewed the editorial together.

  • Competing interests None.

  • Provenance and peer review Commissioned; internally peer reviewed.

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