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WINROP can modify ROP screening praxis: a validation of WINROP in populations in Sörmland and Västmanland
  1. Laila Eriksson1,
  2. Ulrika Lidén2,
  3. Chatarina Löfqvist3,
  4. Ann Hellström3
  1. 1Ophthalmology Department, Västmanland Hospital in Västerås, Västerås, Sweden
  2. 2Ophthalmology Department, Mälarsjukhuset in Eskilstuna, Eskilstuna, Sweden
  3. 3Sahlgrenska Academy at University of Gothenburg, Institute of Neuroscience and Physiology, Gothenburg, Sweden
  1. Correspondence to Dr Laila Eriksson, Department of ophthalmology, Västmanland hospital, Västerås 721 89, Sweden; laila.eriksson{at}, laila4321{at}


Background This study validates the newly developed WINROP algorithm aimed at detecting retinopathy of prematurity (ROP) requiring treatment at an early stage. The study was conducted at two middle-sized hospitals in Sweden, prospectively and retrospectively.

Methods A total of 104 children participated in this study. Their mean gestational age at birth was 28.7 weeks (range, 23.6–32.1 weeks), and their mean birth weight was 1208 g (range, 477–2340 g). Weekly weight measurements were used in WINROP to calculate the risk of developing ROP.

Results 80% of infants (83/104) had no ROP, 15% (16/104) had mild ROP (stage 1 or 2), 5% (5/104) had severe ROP, and 2% (2/104) were treated for ROP. The alarm was registered at an average of 2 weeks postnatal age (range 1–6 weeks).

Conclusions WINROP identified all the infants at risk for developing stage 3 ROP (100% sensitivity) and had a 59% specificity. The alarm was registered several weeks before screening for ROP began. WINROP can be used to complement conventional ROP screening.

  • Child Health (paediatrics)
  • Retina
  • Vision

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