Footnotes

• Correction notice This article has been corrected since it was published Online First. The word ‘gutta’ has been amended to ‘guttae’ in the article title.

• Funding Grants from the National Institutes of Health (EY019874), J Willard and Alice S Marriott Foundation, Edward Colburn, Lorraine Collins, Richard Dianich, Mary Finegan, Barbara and Peter Freeman, Stanley Friedler, MD, Herbert Kasoff, Diane Kemker, Jean Mattison, Lee Silverman, Norman Tunkel, PhD (all to ASJ), and Research to Prevent Blindness (to Wilmer Eye Institute).

• Competing interests None.

• Provenance and peer review Not commissioned; externally peer reviewed.

• Data sharing statement All data are available upon request from the corresponding author.