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Amniotic membrane graft to conjunctival flap in treatment of non-viral resistant infectious keratitis: a randomised clinical study
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  • Published on: 27 July 2017
    Response to Thevi T comments

    Dear Sir
    Thanks for this notification
    1. Preoperative and postoperative characteristics for the CF group are shown in Table 2 (line 13)
    Answer: This was a typing error hoping if it will be corrected to: preoperative and postoperative characteristics for the AMG group are shown in Table 2
    2. The study does not mention about the location postoperatively. How will the site of the ulcer change from central to paracentral and vice versa?
    Answer: Eighteen from twenty patients in each group showed healing of the ulcer, and two cases in each group were sent for keratoplasty (from 4 to 8 days after intervention). So, there is no need to mention size of the ulcer. Regarding site of the ulcer; some paracentral ulcer are creeping and/or enlarging in size to involve the central part.
    Regarding site of the ulcer; some paracentral ulcer are creeping and/or enlarging in size to involve the central part.
    So the description of the ulcer will be changed from peripheral to central.
    There was no need to mention this as the ulcers healed.
    3. There is no mention about the complications studied. Descemetocele and perforations occurred preoperatively.
    Answer: Three cases with perforation and one case with descemetocele were referred to immediate keratoplasty, and other ulcers healed, so there were no complications to be mentioned. Regarding other complications in secondary outcome measures, there were no complications and this was mentio...

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    Conflict of Interest:
    None declared.
  • Published on: 18 July 2017
    Amniotic membrane graft to conjunctival flap in treatment of non-viral resistant infectious keratitis: a randomised clinical study

    Dear Editor,
    I read with interest the above randomised clinical study published by
    Abdulhalim et al in BrJ Ophthal 2015;99:59-63.
    The main outcome measures were location, size and depth of the lesion,
    epithelialisation time and persistence of infection. Secondary outcome
    measures include visual acuity and other complications.

    Table 1 states Demographic data and preoperative characteristics for
    conjunctival flap group.
    Table 2 states Demographic data and preoperative characteristics for
    amniotic transplant group.
    However in the narration in Results-it states preoperative and
    postoperative characteristics for the CF group are shown in Table 1 (line
    5) preoperative and postoperative characteristics for the CF group are
    shown in Table 1. preoperative and postoperative characteristics for the CF
    group are shown in Table 2 (line 13). This is very confusing.

    Table 3 shows a comparison of CF group and AMG. Here the preoperative and
    postoperative characteristics are all in one table.

    The main outcome measures were location. The study does not mention about
    the location postoperatively. How will the site of the ulcer change from
    central to paracentral and vice versa? There is no mention about the size
    and depth of the ulcer- which is also a parameter that was studied.There is
    no mention about the complications studied. Descematocoele and perforations...

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    Conflict of Interest:
    None declared.
  • Published on: 22 March 2016
    Comment on : Amniotic membrane graft to conjunctival flap in treatment of non-viral resistant infectious keratitis: a randomised clinical study
    Dear sir, We read the article by Abdulhalim et al with great interest (1) . The article remind us that both CONJUNCTIVAL FLAP and AMNIOTIC MEMBRANE GRAFT are effective in corneal healing and can be an alternative to keratoplasty in cases of infectious keratitis. However we have some concerns: The way to assess the mean size of ulcer and depth and the healing time in the post operative period would have made the comparis...
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    Conflict of Interest:
    None declared.
  • Published on: 22 March 2016
    Amniotic membrane graft to conjunctival flap in treatment of non-viral resistant infectious keratitis: a randomised clinical study

    Dear Editor; We have read the article entitled "Amniotic membrane graft to conjunctival flap in treatment of non-viral resistant infectious keratitis: a randomised clinical study" by Abdulhalim et al. with interest.1 The authors compare the results of bipedicle conjunctival flap and cryopreserved amniotic membrane graft in the treatment of non-viral infectious keratitis resistant to medical treatment. We want to express...

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    Conflict of Interest:
    None declared.