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  • Diagnosis of an atypical case of ocular toxoplasmosis using the demonstration of intraocular antibody production and the polymerase chain reaction

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Letter to the Editor
Diagnosis of an atypical case of ocular toxoplasmosis using the demonstration of intraocular antibody production and the polymerase chain reaction
  1. M MINIHAN,
  2. P E CLEARY
  1. Department of Ophthalmology, Cork University Hospital and University College, Cork
  2. Department of Medical Microbiology, Cork University Hospital and University College, Cork
  3. Toxoplasma Reference Unit, Public Health Laboratory, St George’s Hospital, Blackshaw Road, London
  1. B CRYAN
  1. Department of Ophthalmology, Cork University Hospital and University College, Cork
  2. Department of Medical Microbiology, Cork University Hospital and University College, Cork
  3. Toxoplasma Reference Unit, Public Health Laboratory, St George’s Hospital, Blackshaw Road, London
  1. R HOLLIMAN
  1. Department of Ophthalmology, Cork University Hospital and University College, Cork
  2. Department of Medical Microbiology, Cork University Hospital and University College, Cork
  3. Toxoplasma Reference Unit, Public Health Laboratory, St George’s Hospital, Blackshaw Road, London
  1. Ms Minihan.

https://doi.org/10.1136/bjo.83.6.753a

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    Editor,—Ocular toxoplasmosis is the most frequent infectious cause of chorioretinal inflammation in immunocompetent individuals.1 Diagnosis is usually made by observing the typical fundus lesion, by detecting the presence of anti-Toxoplasma antibodies in the serum, and by excluding other causes of necrotising fundus lesions.2In unusual cases, invasive procedures may be required to aid diagnosis.3

    CASE REPORT

    A 17 year old white male presented complaining of floaters and reduced visual acuity in the left eye. Visual acuity was 6/9 in the left eye, 6/6 in the right. Examination revealed moderate anterior chamber activity, marked vitritis, and an active retinochoroiditis adjacent to an area of old chorioretinal scarring inferonasal to the optic disc. A diagnosis of ocular toxoplasmosis was suspected, and topical and oral steroids, …

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