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Cell subpopulations in failed human corneal grafts
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Editor,—In the well illustrated paper by Kuffová and co-authors,1 conclusions are presented on the roles of different inflammatory cell phenotypes based on immunohistochemical findings in excised corneal transplants. The detailed pathological findings should be interpreted with caution as insufficient information is presented to support the clinical diagnosis of rejection in some of those patients with graft inflammation.
In several patients in Table 2, and all in Table 3, surface wound healing problems, graft melting, and spontaneous perforation are listed as postoperative complications. However, none of these are …