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  • Unilateral corneal anaesthesia and ulceration following squint surgery in a child with Pendred syndrome and bilateral sixth nerve palsy

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Unilateral corneal anaesthesia and ulceration following squint surgery in a child with Pendred syndrome and bilateral sixth nerve palsy
  1. R V Wintle1,
  2. Y F Choong2,
  3. D E Laws3
  1. 1Eye Unit, Southampton General Hospital, Tremona Road, Southampton SO22 5DS, UK
  2. 2Eye Unit, University Hospital of Wales, Cardiff, UK
  3. 3Department of Ophthalmology, Singleton Hospital, Swansea, UK
  1. Correspondence to: Mr Richard V Wintle, Eye Unit, Southampton General Hospital, Tremona Road, Southampton SO22 5DS, UK; richardwintle67{at}yahoo.com

https://doi.org/10.1136/bjo.87.9.1192

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    We present a 4 year old child with Pendred syndrome and bilateral sixth nerve palsy. To our knowledge this association has not been previously reported. In addition, this patient developed unilateral corneal ulceration with associated corneal anaesthesia following squint surgery. We will discuss the pathophysiology of this unusual complication following squint surgery.

    Case report

    This patient presented when he was 6 months old with right convergent squint. He was diagnosed with Pendred syndrome (sensorineural hearing loss and thyroid dysfunction) by the paediatricians and the otolaryngologists following abnormal thyroid function tests and a computed tomograph (CT) scan of the temporal bones showing Mondini malformations of both cochleas. At presentation his visual acuities were 6/60 right eye and 6/36 left eye using the Cardiff acuity cards. He had bilateral alternating esotropia with an inability to abduct either eye. There was no globe retraction or abnormal lid movements and a magnetic resonance imaging (MRI) …

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