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Ultrahigh resolution optical coherence tomography of birdshot retinochoroidopathy
  1. A J Witkin1,
  2. J S Duker1,
  3. T H Ko2,
  4. J G Fujimoto2,
  5. J S Schuman3
  1. 1New England Eye Center, Tufts-New England Medical Center, Tufts University, Boston, MA, USA
  2. 2Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA
  3. 3UPMC Eye Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
  1. Correspondence to: Jay S Duker MD, Ophthalmology Department, Tufts-New England Medical Center, 750 Washington Street, Boston, MA 02111, USA; jdukertufts-nemc.org

https://doi.org/10.1136/bjo.2005.076570

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    Birdshot retinochoroidopathy is a rare inflammatory eye disease with typical clinical presentation and strong association with the HLA-A29 allele. Characteristic appearances on fluorescein angiogram (FA), indocyanine green (ICG) angiography, and electroretinogram (ERG) have been described.1 However, histopathology of the disease has been rare.2,3 The following case is an example of birdshot retinochoroidopathy imaged with ultrahigh resolution optical coherence tomography (UHR-OCT), capable of 3 µm axial resolution.4 UHR-OCT is able to clearly delineate individual intraretinal layers (fig 1).

    Figure 1

     Ultrahigh resolution optical coherence tomography image from a normal eye. The intraretinal layers are labelled: NFL, nerve fibre layer, GCL, ganglion cell layer, IPL, inner plexiform layer, INL, inner nuclear layer, OPL, outer plexiform layer, ONL, outer nuclear layer, IS/OS, photoreceptor inner/outer segment junction, RPE, retinal pigment epithelium.

    Case report

    A 64 year old man presented to the New England Eye Center (NEEC) for progressive visual deterioration despite …

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    Footnotes

    • Supported in part by NIH contracts RO1-EY11289-16, R01-EY13178, and P30-EY13078, NSF contract ECS-0119452, Air Force Office of Scientific Research contract F49620-98-1-0139, Medical Free Electron Laser Program contract F49620-01-1-0186 and by Carl Zeiss Meditec.

      JGF and JSS receive royalties from intellectual property licensed by MIT to Carl Zeiss Meditec. JGF and JSS receive research support from Carl Zeiss Meditec.

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