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'The Epidemiology of Rhegmatogenous Retinal Detachment - Geographic Variation and Clinical Associations'
  1. Danny Mitry (mitryd{at},
  2. David G Charteris,
  3. Brian W Fleck,
  4. Harry Campbell,
  5. Jaswinder Singh
  1. Princess Alexandra Eye Pavilion, United Kingdom
  2. Moorfields Eye Hosptial, United Kingdom
  3. Princess Alexandra Eye Pavilion, United Kingdom
  4. University of Edinburgh, United Kingdom
  5. Princess Alexandra Eye Pavilion, United Kingdom


    Rhegmatogenous retinal detachment (RRD) is a potentially blinding condition. Obtaining an accurate estimate of RRD incidence in the population is essential in understanding the healthcare burden related to this disorder.

    Methods: A systematic review of all population-based epidemiology studies of RRD published between January 1970 and January 2009 from Medline database searches was performed.

    Results: RRD incidence demonstrates significant geographic variation and has been reported between 6.3 and 17.9 per 100,000 population. For studies with a sample size >300 the median annual incidence per 100,000 population was 10.5 (IQR 8.1 - 13.2) and mean proportion of bilateral RRD was 7.26%. Overall, the mean prevalence of lattice degeneration was 45.7% (SD–20.3%) and myopia was 47.28% (SD-12.59%).

    Conclusions: Estimates of RRD incidence have varied three-fold but inclusion criteria and other design features have differed across studies making direct comparisons difficult. The overall incidence of RRD is not yet well established, more incidence studies of adequate methodology are needed to explore temporal changes in incidence. RRD incidence varies with ethnicity and is strongly associated with increasing age, myopia and certain vitreo-retinal degenerations. Due to changes in cataract surgery trends, the proportion of pseudophakic RRD presenting to specialised centres appears to be increasing.

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