Aim: To investigate the frequency and risk factors of macular hole (MH) formation after rupture of a retinal arterial macroaneurysm.
Methods: Fifty-six eyes from 56 patients with rupture of a retinal arterial macroaneurysm with or without an MH (MH and non-MH groups, respectively) were reviewed. Frequency and risk factors related to MH formation were assessed, with risk factors including age; sex; distance from the macroaneurysm to the fovea; incidence of hemorrhages involving the macula such as preretinal, subinternal limiting membrane (subILM), subretinal, and vitreous; and vitreous surgery. MH formation in these patients was recorded and analyzed.
Results: Of the 56 eyes reviewed, 7 (12.5%) had an MH after rupture of the retinal arterial macroaneurysm. The incidence of subretinal and subILM hemorrhages involving the macula was significantly greater in the MH group than in the non-MH group (p = 0.037 and 0.045, respectively).
Conclusion: These results suggest that the presence of subretinal and subILM hemorrhages after rupture of a retinal arterial macroaneurysm may contribute to formation of an MH.
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