Article Text

other Versions

Download PDFPDF

Trachoma mass treatment with azithromycin 1.5% eye drops in Cameroon: feasibility, tolerance and effectiveness
  1. Pierre Huguet1,
  2. Lucienne Bella2,
  3. Ellen Einterz3,
  4. Pablo Goldschmidt4,
  5. Philippe Bensaid5
  1. 1 World Health Organization, Switzerland;
  2. 2 Ministry of Health, Cameroon;
  3. 3 Kolofata District Service, Cameroon;
  4. 4 National Center of Ophthalmology of the Quinze-Vingts, France;
  5. 5 Ophtalmo Sans frontières, France
  1. * Corresponding author; email: p.huguet{at}


Background/aims: An epidemiological study carried out in 2006 indicated the existence of a high prevalence of blinding trachoma in the Kolofata Health District, Far North Region, Cameroon. As a result, the national blindness control program of Cameroon instituted a trachoma elimination programme using the SAFE strategy.

Methods: A campaign to treat the entire district population with azithromycin 1.5% eye drops was undertaken in February, 2008. To measure the effectiveness of treatment on the prevalence of active trachoma, two epidemiological studies were conducted on a representative sample of children aged between 1 and 10 years. The first study was performed just prior to the treatment campaign and the second study was performed one year later.

Results: The prevalence of active forms of trachoma (TF + TF/TI) dropped from 31.5% (95%CI 26.4-37.5) before treatment to 6.3% (95%CI 4.1-9.6) one year after treatment; a reduction of nearly 80%.

There were no reports of serious or systemic side effects. Tolerance was excellent. No treatment was interrupted.

Conclusion: Mass treatment with azithromycin 1.5% eye drops is therefore feasible, well tolerated, and effective.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


Linked Articles

  • At a glance
    Harminder S Dua Arun D Singh