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Spectral domain optical coherence tomography for higher precision in the evaluation of vitreoretinal adhesions in exudative age-related macular degeneration
  1. Ilse Krebs,
  2. Carl Glittenberg,
  3. Florian Zeiler,
  4. Susanne Binder
  1. Department of Ophthalmology Rudolf Foundation Clinic and The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery, Vienna, Austria
  1. Correspondence to Dr Ilse Krebs, Department of Ophthalmology, Rudolf Foundation Clinic, Juchgasse 25, 1030 Vienna, Austria; ilse.krebs{at}


Aim The role of changes at the vitreoretinal interface and vitreomacular traction forces in pathogenesis, and the course of exudative age-related macular degeneration (AMD) need further exploration. This study examines the localisation of adhesion and the direction of traction lines in eyes with exudative AMD.

Methods The cubes 512×128 of Cirrus optical coherence tomography (OCT) and volume scans of Spectralis OCT were reviewed in a consecutive series of patients presenting between December 2008 and March 2009 with vitreomacular adhesion in exudative AMD.

Results 30 eyes of 25 patients with exudative AMD and vitreomacular adhesion were studied. 50% had type III lesions, 46.7% occult and 3.3% predominantly classic lesions. The localisation of the adhesion corresponded in 100% with the area of the neovascularisation (CNV), in 73.3% traction directed towards the CNV and in 83.3% towards the optic disc could be noted. Spectral domain OCT and 3D visualisation enabled clearer localisation of vitreomacular adhesion and definition of resulting traction lines.

Conclusion There is a high prevalence of type III lesions within eyes with vitreomacular adhesions, and complete correspondence between the location of the adhesion and the CNV. There is also a high incidence of vitreopapillary adhesion in these cases, suggesting a possible role in pathogenesis.

  • Vitreomacular traction
  • age-related macular degeneration
  • Optical Coherence Tomography
  • spectral domain OCT
  • choroidal neovascularisation
  • vitreous
  • retina
  • imaging

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  • Presented in part at the annual meeting of the Association for Research in Vision and Ophthalmology, Fort Lauderdale, Florida, 7 May 2009 (5245/A106).

  • Funding Ludwig Boltzmann Institute of Retinology and Biomicroscopic Lasersurgery.

  • Competing interests CG is a consultant for Carl Zeiss Meditec and for Maxon Computer Inc.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.