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Nanophthalmos: quantitative analysis of anterior chamber angle configuration before and after cataract surgery
  1. Masaaki Seki,
  2. Takeo Fukuchi,
  3. Jun Ueda,
  4. Kieko Suda,
  5. Tomoko Nakatsue,
  6. Yoko Tanaka,
  7. Tetsuya Togano,
  8. Susumu Yamamoto,
  9. Hiroaki Hara,
  10. Haruki Abe
  1. Department of Ophthalmology, Division of Ophthalmology and Visual Science, Graduated School of Medical and Dental Sciences, Niigata University, Niigata, Japan
  1. Correspondence to Dr Masaaki Seki, Seki Eye Clinic, 1-30-1 Kobari, Niigata 950-2022, Japan; masaaki.seki{at}


Background/aims To analyse quantitatively the anterior segment configuration in eyes with nanophthalmos before and after cataract surgery.

Methods This was a retrospective, non-comparative, interventional case series. Eleven eyes in eight patients with nanophthalmos who underwent phacoemulsification and intraocular lens implantation were identified from the department's surgical log, and their clinical records were retrospectively reviewed. Main outcome measures were as follows: visual acuity, intraocular pressure (IOP), axial length and the following ultrasound biomicroscopy parameters: angle opening distance at 500 μm anterior to the scleral spur (AOD500), trabecular–iris angle (TIA) and trabecular ciliary process distance.

Results The mean axial length of the eyes was 17.3±1.7 mm. AOD500 and TIA increased after cataract surgery (p<0.005). Smaller axial length, AOD500 and TIA before cataract surgery were observed in eyes with preoperative IOP elevation than those without preoperative IOP elevation (p<0.05). Lower postoperative IOP was correlated with greater AOD500 and TIA before cataract surgery (p<0.05).

Conclusions Cataract surgery deepened the anterior chamber and widened the anterior chamber angle in nanophthalmic eyes. Cataract surgery may have beneficial effects on IOP in eyes with nanophthalmos.

  • Glaucoma

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  • Funding This work was supported in part by grants-in-aid for scientific research KAKENHI 23592556 (to TF), Japan Society for the Promotion of Science. Governmental (not commercial).

  • Competing interests None.

  • Ethics approval Ethics approval was provided by the Graduated School of Medical and Dental Sciences, Niigata University.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement Data are available from the corresponding author upon request.