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Corneal wound healing after laser vision correction
  1. Leopoldo Spadea1,
  2. Daniele Giammaria2,
  3. Paolo Trabucco1
  1. 1Department of Biotechnology and Medical-Surgical Sciences, ‘Sapienza’ University of Rome, Latina, Italy
  2. 2Department of Ophthalmology, Ospedali Riuniti Marche Nord, Fano-Pesaro, Italy
  1. Correspondence to Professor Leopoldo Spadea, Department of Biotechnology and Medical-Surgical Sciences, ‘Sapienza’ University of Rome, Via Benozzo Gozzoli 34, Rome 00142, Italy; leopoldo.spadea{at}


Any trauma can trigger a cascade of responses in tissues, with the purpose of safeguarding the integrity of the organ affected by the trauma and of preventing possible damage to nearby organs. Subsequently, the body tries to restore the function of the organ affected. The introduction of the excimer laser for keratorefractive surgery has changed the treatment landscape for correcting refractive errors, such as myopia, hyperopia, and astigmatism. In recent years, with the increased understanding of the basic science of refractive errors, higher-order aberrations, biomechanics, and the biology of corneal wound healing, a reduction in the surgical complications of keratorefractive surgery has been achieved. The understanding of the cascade of events involved in the corneal wound healing process and the examination of how corneal wound healing influences corneal biomechanics and optics are crucial to improving the efficacy and safety of laser vision correction.

  • Cornea
  • Treatment Lasers
  • Wound healing

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