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Rhegmatogenous retinal detachment presentation and surgery in uveitic eyes
  1. Tafadzwa Young-Zvandasara1,2,3,
  2. David Brunner1,3,
  3. Sarah Welch1,3,
  4. Joanne L Sims1,3,
  5. Clairton De Souza1,3,
  6. William J Cunningham1,3,
  7. Rachael L Niederer1,3
  1. 1Ophthalmology, The University of Auckland Faculty of Medical and Health Sciences, Auckland, New Zealand
  2. 2Newcastle Eye Centre, Royal Victoria Infirmary, Newcastle, UK
  3. 3Greenlane Clinical Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
  1. Correspondence to Dr Tafadzwa Young-Zvandasara, Ophthalmology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland 1051, New Zealand; tpzvandas{at}hotmail.com

Abstract

Background/aims To explore the occurrence, uveitis activity, features, rate of proliferative vitreoretinopathy (PVR) and outcomes following rhegmatogenous retinal detachment (RRD) in a large tertiary referral uveitis service.

Methods Retrospective analysis of subjects attending between 2008 and 2019. Multivariate analysis of risk factors for RRD was calculated. Nelson-Aalen plots were used to demonstrate cumulative risk of RRD. Outcomes of RRD surgery and prognostic indicators were analysed.

Results Two thousand four hundred and forty-seven (2447) subjects (3516 eyes) with uveitis included. The mean follow-up was 5.7 years (19 767 eye-years); 56 eyes developed a RRD (1.6%). Thirty-two eyes had surgery in our unit. Risk factors for RRD were posterior uveitis or panuveitis (HR 3.386, p<0.001), male gender (HR 2.045, p=0.029) and infectious aetiology (HR 1.942, p=0.044). PVR was present in six (18.8%) eyes at presentation, and a further four (12.5%) developed it after the primary surgery. Final follow-up data showed 16 (50%) moderate or severe visual loss, although 29 (90.6%) had anatomical reattachment without oil in situ.

Conclusions There is a high rate of RRD in uveitis eyes. This is accompanied by high rates of PVR and redetachment. Anatomical success was high, but visual outcomes remain unpredictable.

  • retina
  • ciliary body
  • iris
  • choroid

Data availability statement

Data are available upon reasonable request. Data are deidentified participant data.

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Data availability statement

Data are available upon reasonable request. Data are deidentified participant data.

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Footnotes

  • Contributors All authors provided a final review and approved the manuscript before submission. TY-Z, RLN, SW, DB, JLS, WJC and CDS conceived and designed the study. TY-Z, SW, RLN, JLS and WJC collected the clinical data. RLN and TY-Z analysed and interpreted the data. TY-Z, RLN and CDS wrote the initial draft. TY-Z, RLN, DB, SW, JLS, CD and WJC judged the data interpretation and edited the manuscript. SW supervised the study.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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