Article Text

Download PDFPDF
Clinical outcomes of penetrating canaloplasty in patients with traumatic angle recession glaucoma: a prospective interventional case series
  1. Huanhuan Cheng1,
  2. Wenqing Ye1,2,3,
  3. Shaodan Zhang1,2,3,
  4. Yanqian Xie1,2,3,
  5. Juan Gu1,
  6. Rongrong Le1,2,3,
  7. Yuxuan Deng1,
  8. Cheng Hu4,
  9. Zhenquan Zhao1,2,
  10. Zhisheng Ke1,2,
  11. Yuanbo Liang1,2,3
  1. 1Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China
  2. 2National Clinical Research Center for Ocular Diseases, Wenzhou, Zhejiang, China
  3. 3Institute of Glaucoma, Wenzhou Medical University, Wenzhou, Zhejiang, China
  4. 4Department of Ophthalmology, Wuhan General Hospital of Guangzhou Command, Wuhan, Hubei, China
  1. Correspondence to Dr Yuanbo Liang, Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China; yuanboliang{at}126.com

Abstract

Background/aim To evaluate the clinical outcomes of penetrating canaloplasty in traumatic angle recession glaucoma at 1 year.

Methods Patients with angle recession glaucoma underwent penetrating canaloplasty, a new Schlemm’s canal-based internal drainage procedure, which creates a direct canal for flow of aqueous humour from the anterior chamber to the ostia of Schlemm’s canal via a window created at the corneal scleral bed without use of antimetabolites. Postoperative intraocular pressure (IOP), number of glaucoma medications, and procedure-related complications were evaluated. Success was defined as an IOP ≤21 mm Hg without (complete) or with (qualified) use of glaucoma medication.

Results Forty eyes in 40 patients with angle recession glaucoma underwent successful circumferential catheterisation. The mean patient age was 42±13 years. In patients with penetrating canaloplasty that was deemed to be completely successful, the mean IOP decreased from a preoperative value of 37.8±12.3 mm Hg on 3.3±1.2 anti-glaucoma medications to 18.5±6.4 mm Hg on 1.2±1.4 medications, 14.9±4.6 mm Hg on 0.1±0.5 medications, 15.7±5.4 mm Hg on 0.1±0.4 medications and 14.8±3.6 mm Hg on 0.1±0.5 medications at 1, 3, 6 and 12 months postoperatively (p<0.05). Complete success was achieved in 35/40 eyes (87.5%) at 6 months and in 34/38 (89.5%) at 12 months. Hyphema (18/40, 45.0%) and transient IOP elevation (≥30 mm Hg, 9/40, 22.5%) were the most common postoperative complications.

Conclusion Penetrating canaloplasty significantly reduces IOP and has a high success rate in angle recession glaucoma.

Trial registration number ChiCTR1900020511.

  • Glaucoma
  • Trauma

Data availability statement

Data are available on reasonable request. Not applicable.

Statistics from Altmetric.com

Data availability statement

Data are available on reasonable request. Not applicable.

View Full Text

Footnotes

  • HC and WY contributed equally.

  • Contributors Study design: YL, SZ and HC; data acquisition: HC, SZ, JG, CH, YX, WY, RL and YD; writing, reviewing and editing: HC, YL and SZ; technical and material support: ZZ and ZK.The corresponding author attests that all listed authors meet authorship criteria and that no others meeting the criteria have been omitted. YL is the guarantor.

  • Funding This study was supported by National Key R&D Program of China 2020YFC2008200,Leading Talents in Science and Technology of Zhejiang Ten Thousand Talents Program 2021R52012 and Key Research and Development Program of Zhejiang 2022C03112.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.